I've just started a new job at the University of Leeds, as a postdoc for Sheena Radford in the Astbury Centre for Structural and Molecular Biology. I'm looking at the folding pathways of bacterial immunity proteins (about which I'll write a bit at some point in the future), so I'm going to have to put a new picture up here when I find one. All I can really say about the project right now is that it's looking at the influence of function on folding, and the nature of Im7 and Im9's folding intermediate. There's a relevant review in a recent Current Opinion in Structural Biology.
I may not have got around to sorting out this page yet, but the Radford lab website is clearly more organised - I'm already online here. Better get around to writing this then...
I did my PhD at the University of Sheffield, working for Jon Waltho and Rosie Staniforth, doing research into the mechanisms which underly amyloidosis, a process involved in several major neurodegenerative diseases. More specifically, I've mapped the structure of the amyloid fibrils formed by stefin B, a member of the cystatin superfamily. The NMR group's webpages.
I've tried to write a description of what I did for my PhD project that's intelligible to people who aren't structural biologists. I've tried to link to places that will explain some of the concepts involved. A protein folding bit will be coming up soon.
Other useful bits:
My CV (PDF)
There's also an animation of the domain swapping process (~220k gif) - created with the help of the Yale Morph Server. It's pretty meaningless unless you know what it is, but hey, that's life... I have a bigger one (ahem) if you want to use it - I've also written a description of how I made it, along with advice on making your own.
There's a bunch of work-related pictures in the photo section of this site. Or at least, there will be at some stage.
